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[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate

2492423-29-5 C13H19N3O7

About [(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate

[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate (CAS 2492423-29-5) is a chemical compound with the molecular formula C13H19N3O7 and a molecular weight of 329.31 g/mol. It has an InChIKey of HTNPEHXGEKVIHG-QCNRFFRDSA-N.

Properties

[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate molecular structure
CAS Number
2492423-29-5
Formula
C13H19N3O7
Molecular Weight
329.31 g/mol
IUPAC Name
[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate
InChI Key
HTNPEHXGEKVIHG-QCNRFFRDSA-N

Also Known As

[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate is also known as molnupiravir, Lagevrio, Eidd 1931-isopropyl ester, N4-Hydroxycytidine, 5'-isopropyl ester, Molnupiravir [INN], Molnupiravir [USAN], among other names.

molnupiravir EIDD-2801 Lagevrio MK-4482 EIDD 2801 Uridine, 4-oxime, 5'-(2-methylpropanoate) YA84KI1VEW Eidd 1931-isopropyl ester EIDD-1931 ISOPROPYL ESTER N4-Hydroxycytidine, 5'-isopropyl ester

Description

Molnupiravir is a nucleoside analogue that is N4-hydroxycytidine in which the 5'-hydroxy group is replaced by a (2-methylpropanoyl)oxy group. It is the prodrug of the active antiviral ribonucleoside analog N4-hydroxycytidine (EIDD-1931), has activity against a number of RNA viruses including SARS-CoV-2, MERS-CoV, and seasonal and pandemic influenza viruses. It is currently in phase III trials for the treatment of patients with COVID-19. It has a role as an anticoronaviral agent, an antiviral drug and a prodrug. It is a ketoxime, an isopropyl ester and a nucleoside analogue. It is functionally related to a N(4)-hydroxycytidine.

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Also Available From

Suppliers listing [(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate on PubChem, courtesy of the National Library of Medicine. Listed for reference, not verified by us.

Key Organics/BIONET UK

United Kingdom · Cat. no. AS-84465

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Biosynth UK

United Kingdom · Cat. no. AE176721

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Fluorochem UK

United Kingdom · Cat. no. F987085

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